Ilex paraguariensis A. St. -Hil.: a promising source of phenolic compounds with bioactive properties
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Ilex paraguariensis A. St. -Hil. (yerba mate) is a tree widely cultivated in South America, and
commonly used for the production of beverages such as chimarrão, tereré, and mate tea. The
bioactive composition of its leaves has been associated with many benefít health effects for
the human bodyl11. It is estintated that more than a Jiter ofthese drinks are consumed daily by
approximately 30% of the South American populafionllJ Throughout the industrial
processing of this plant for beverage production an enormous amount of by-products are
generated, as also during the raw material harvest, in which about 5 tons per hectare of solid
residues from the Jarger-diameter yerba branches are discarded in the soiJPI. Severa) research
studies have been carried out regarding the use of these by-products by the food industry,
being a very interesting and promising alternative for obtaining added-value bioactive
compoundsll] This work aimed to compare the phenolic composition and bioactive potential
of dehydrated yerba mate extracts (EMNP) and yerba mate by-products (EMP) obtained from
an industrial production in the state of Paraná (Brazil). The individual phenolic profile was
determined by HPLC-DAD-ESIJMS and lhe bioactive potential was assessed in
hydroethanolic extracts through in vitro tests for antioxidant, antimicrobial, anti-inflammatory,
and cytotoxicity activity. ln total, seven phenolic compounds were tentatively identified, in
which six phenolic acids: 4-0-caffeoylquinic acid, 5-0
