Antioxidant activity and phenolic compounds in decoction, infusion and hydroalcoholic extract of Origanum vulgare L.
Artigo de Conferência
Visão geral
Pesquisas
Ver Todos
Visão geral
resumo
Reactive species, including free radicals, have been implicated in ageing and
various diseases [1]. The human body possesses an antioxidant defense system
that acts in the detoxification and elimination of those species. Nevertheless,
natural matrices can give an exogenous contribution, providing antioxidant
biomolecules such is the case of phenolic compounds [2]. Origanum vu/gore L.
(oregano) could be one of those matrices since various studies already reported
the antioxidant potential of its methanolic extract [for example, 3] and essential
oils [for example, 4]. Nonetheless, the reports using aqueous extracts are scarce
[5], mainly in decoction or infusion preparations traditionally used to their
digestive, expectorant, antiseptic and antispasmodic properties.
In the present work, the antioxidant properties (reducing power- RP, free
radica ls scavenging activity- RSA and lipid peroxidation inhibition- LPI) and
phenolic compounds of the infusion, decoction and hydroalcoholic extract of
oregano (obtained from Soria Natural, Spain) were evaluated and compared.
The infusion and decoction presented similar RP and RSA, showing the
decoction higher LPI. Both preparations gave higher antioxidant activity than
the hydroalcoholic extract. Twenty-two phenolic compounds were identified by
HPLC-OAO-ESI/MS: seven phenolic acids (caffeoylquinic, syringic, protocatequic
and rosmarinic acids, and derivatives), six flavonols (quercetin, kaempferol and
myrecitrin derivatives), five flavones (apigenin and luteolin derivatives), one
flavanonol (taxifolin) and one flavanone (eriodictyol). Rosmarinic acid and
luteolin-7-0 -glucoside were the main phenolic acid and flavonoid, respectively,
in all the preparations. Data obtained provide more scientific evidences to the traditional medicinal uses of oregano, mainly in the treatment of oxidative stress-associated diseases.
