Infusions obtained from two medicinal plants as a source of polyphenols with antibacterial activity

Several researches are now oriented towards studying natural molecules of plant origin. In Algeria, many herbs are used as traditional remedies to treat different diseases. In this context, the phenolic compounds of the aqueous extracts, obtained by infusion, of two plant species, Saccocalyx satureioides Coss.& Dur and Limoniastrum guyonianum Boiss., from the Algerian flora, were identified and quantified by HPLC-DADESI/ MS, and their antibacterial activity was evaluated against clinical isolates. The results indicate the presence of several phenolic acids, in particular, derivatives of caffeic acid with glycosylated flavonoids. While for S. satureioides 13 phenolic compounds were identified and the rosmarinic acid was the most abundant phenolic acid, L. guyonianum showed a high abundance of myricetin and derivatives such as myricetin-3-O-glucoside and myricetin-O-rhamnoside among the eight molecules detected. The antibacterial activity of the infusions was significant with MIC values between 2.5 and 20 mg/mL, however, L. guyonianum had the highest activity on all the tested bacteria. Staphylococcus aureus and Pseudomonas aeruginosa were the most sensitive and the most resistant strains, respectively. Consequently, the studied plant species are sources of natural antibacterial substances that can be used to fight against pathogenic microorganisms.

Infusions obtained from two medicinal plants as a source of polyphenols with antibacterial activity Artigo de Conferência