Urinary levels of monohydroxyl PAH metabolites in portuguese firefighters: background levels and impact of tobacco smoke
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Firefighting occupational exposure is classified as possible
carcinogen to humans by the International Agency for Research
on Cancer and the US National Institute for Occupational Safety
and Health [1,2].
Tobacco smoke is a very important factor in the assessment of
occupational exposure of workers, since the prolonged exposure
to tobacco smoke is by itself the major cause of lung cancer [3].
The consumption of tobacco is responsible for the exposure to
many smoke components including more than sixty known
carcinogens, including some polycyclic aromatic hydrocarbons
(PAHs) [4].
PAHs are ubiquitous compounds formed during pyrolysis or
incomplete combustion of organic matter, being well-known for
their toxic, mutagenic, and carcinogenic properties to humans
[5,6]. So far, the impact of tobacco smoke on firefighters’ total
exposure to PAHs is very limited.
Firefighting occupational exposure is classified as possible carcinogen to humans by the International
Agency for Research on Cancer and the US National Institute for Occupational Safety and Health [1,2].
Full monitoring of firefighters’ exposure to PAHs via all exposure routes should be performed through
the quantification of their internal dose. The consumption of tobacco is responsible for the exposure to
many smoke components including more than sixty known carcinogens, including polycyclic aromatic
hydrocarbons (PAHs) [3]. PAHs are ubiquitous compounds formed during pyrolysis or incomplete
combustion of organic matter, being well known for their toxic, mutagenic, and carcinogenic properties
to humans [4,5]. So far, the impact of tobacco smoke on firefighters’ total exposure to PAHs is very
limited.
