Biological activity screening of plant oils for skincare applications
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Essential and vegetables oils are both types of oils derived from plants, but they have distinct characteristics and uses. Essential oils are a precious source of secondary metabolites (mainly polyphenols, alkaloids and terpenes) potentially endowed with a plethora of biological activities. Vegetable oils, also known as plant oils, are lipidic extracts derived from plants that are commonly used for cooking, cosmetic formulations, and various industrial applications. The development of high-added-value products from the essential and vegetable oils industries can be considered a priority due to their broad range of bioactive compounds. Those bioactive compounds could be used for human consumption, medicinal uses and other health products applications, including cosmetics. The aim of this work was to explore the biological potential of commercially available oils. We studied plants that have been traditionally used due to their antimicrobial, anti-inflammatory and antioxidant activities. Moringa oleifera Lam. (Moringaceae family), Lavandula angustifolia and Ocimum kilimandscharicum Gürke (Lamiaceae family), Spirostachys africana Sond. (Euphorbiaceae family), Chrysopogon zizanioides and Cymbopogon citratus (DC.) Stapf (Poaceae family), Corymbia citriodora (Hook.) K.D.Hill & L.A.S.Johnson and Eucalyptus globulus (Myrtaceae family) were the species studied. The antiproliferative potential was evaluated against HaCaT and HFF-1 cells using the sulphorodamine B colourimetric assay. The antioxidant activity was assessed throught DPPH and TBARS assays. The antimicrobial activity was tested against several bacterial and fungal strains using the broth microdilution method. Additionally, the anti-inflammatory capacity through the measurement of oils capacity to inhibit the formation of the nitric oxide in a murine macrophage cell line. Ongoing research is being conducted to further explore the therapeutic properties and potential health benefits of the eight oils extracted from plant materials, emphasizing their use and applications in promoting well-being.
