This study investigates the impact of hemodynamics on real intracranial aneurysms (IAs) using experiments and
computational fluid dynamics (CFD) simulations. A particle tracking velocimetry (PTV) approach was used to
study the vortical structures inside a real aneurysm and validate numerical simulations performed at a steady
regime for different flow rates. Moreover, this and two additional patient-specific cases have been numerically
analyzed, focusing on flow patterns, wall shear stress (WSS), relative residence time (RRT), and oscillatory shear
index (OSI) for transient studies. For the transient simulations, vorticity profiles indicated significant rotation of
fluid particles in the neck and outlet arteries. TAWSS analysis revealed high WSS values in the bifurcation zone,
neck, and middle cerebral artery (MCA), with variations among the patients. OSI and RRT plots provided insights
into disturbed flow patterns, low or oscillatory WSS areas, and regions with prolonged residence time. This study
shows great potential for combining PTV and CFD to obtain detailed insights into flow structures in aneurysms,
which are crucial to developing effective treatments and interventions for IA management.
