Wound healing, a complex physiological process orchestrating intricate cellular and molecular
events, seeks to restore tissue integrity. The burgeoning interest in leveraging the therapeutic
potential of natural substances for advanced wound dressings is a recent phenomenon. Notably,
Sericin, a silk-derived protein, and Chelidonium majus L. (C. majus), a botanical agent, have emerged as
compelling candidates, providing a unique combination of natural elements that may revolutionize
conventional wound care approaches. Sericin, renowned for its diverse properties, displays unique
properties that accelerate the wound healing process. Simultaneously, C. majus, with its diverse
pharmacological compounds, shows promise in reducing inflammation and promoting tissue regeneration.
As the demand for innovative wound care solutions increases, understanding the therapeutic
potential of natural products becomes imperative. This review synthesizes current knowledge on
Sericin and C. majus, envisioning their future roles in advancing wound management strategies. The
exploration of these natural substances as constituents of wound dressings provides a promising
avenue for developing sustainable, effective, and biocompatible materials that could significantly
impact the field of wound healing.
